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Fish skin collagen and extraction of small peptide

Common fish skin collagen extraction methods have hot water method, acid-base extraction, enzymatic extraction, salt extraction, and mixed extraction, fish skin collagen preparation process is similar, the first add salt to rid of neither collagen, by centrifugation, washed with water to obtain crude collagen; addition of acid swollen, and then homogenizing, vacuum filtration then obtained collagen solution. Depending on the different extraction method, fish skin collagen extraction rate ranging from 10 to 20%.